IFN-β improves BCG immunogenicity by acting on DC maturation

Given the variable protective efficacy provided by Mycobacterium bovis bacillus Calmette-Guérin (BCG), there is an urgent need to develop new vaccines against tuberculosis. As dendritic cells (DC) play a critical role in initiating and regulating a protective T cell response against the pathogens, t...

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Bibliographische Detailangaben
Hauptverfasser: Giacomini, Elena, Remoli, Maria Elena, Gafa, Valérie, Pardini, Manuela, Fattorini, Lanfranco, Coccia, Eliana M.
Format: Artigo
Sprache:Inglês
Veröffentlicht: The Society for Leukocyte Biology 2009
Schlagworte:
Extracellular Mediators and Effector Molecules
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2718805/
https://ncbi.nlm.nih.gov/pubmed/19056860
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1189/jlb.0908583
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