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Immunostaining evidence for PI(4,5)P(2) localization at the leading edge of chemoattractant-stimulated HL-60 cells

It is well known that in fMLP-stimulated neutrophils, phosphatidyl inositol 3,4,5-trisphosphate [PI(3,4,5)P(3)] localizes at the leading edge of the cells. However, no effort has been made to study the PI 4,5-bisphosphate [PI(4,5)P(2)] distribution in these cells. In fact, it has been suggested that...

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Detalhes bibliográficos
Main Authors: Sharma, Ved P., DesMarais, Vera, Sumners, Colin, Shaw, Gerry, Narang, Atul
Formato: Artigo
Idioma:Inglês
Publicado em: The Society for Leukocyte Biology 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2718804/
https://ncbi.nlm.nih.gov/pubmed/18477691
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1189/jlb.0907636
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