Multi-tissue coexpression networks reveal unexpected subnetworks associated with disease

BACKGROUND: Obesity is a particularly complex disease that at least partially involves genetic and environmental perturbations to gene-networks connecting the hypothalamus and several metabolic tissues, resulting in an energy imbalance at the systems level. RESULTS: To provide an inter-tissue view o...

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Detalhes bibliográficos
Main Authors: Dobrin, Radu, Zhu, Jun, Molony, Cliona, Argman, Carmen, Parrish, Mark L, Carlson, Sonia, Allan, Mark F, Pomp, Daniel, Schadt, Eric E
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2009
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2718521/
https://ncbi.nlm.nih.gov/pubmed/19463160
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/gb-2009-10-5-r55
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