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Polymorphisms and Haplotypes of Acid Mammalian Chitinase Are Associated with Bronchial Asthma
Rationale: Chitinases are enzymes that cleave chitin, a polysaccharide contained in many parasites of humans. Recent studies in mouse models of bronchial asthma have shown that acid mammalian chitinase (AMCase) is involved in the pathophysiology of asthma. It acts downstream of interleukin-13; inhib...
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| Main Authors: | , , , , , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
American Thoracic Society
2005
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2718453/ https://ncbi.nlm.nih.gov/pubmed/16179638 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1164/rccm.200506-890OC |
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