Polymorphisms and Haplotypes of Acid Mammalian Chitinase Are Associated with Bronchial Asthma

Rationale: Chitinases are enzymes that cleave chitin, a polysaccharide contained in many parasites of humans. Recent studies in mouse models of bronchial asthma have shown that acid mammalian chitinase (AMCase) is involved in the pathophysiology of asthma. It acts downstream of interleukin-13; inhib...

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Bibliografiset tiedot
Päätekijät: Bierbaum, Sibylle, Nickel, Renate, Koch, Anja, Lau, Susanne, Deichmann, Klaus A., Wahn, Ulrich, Superti-Furga, Andrea, Heinzmann, Andrea
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: American Thoracic Society 2005
Aiheet:
A. Asthma and Allergy
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC2718453/
https://ncbi.nlm.nih.gov/pubmed/16179638
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1164/rccm.200506-890OC
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