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A single modular serine protease integrates signals from pattern-recognition receptors upstream of the Drosophila Toll pathway
The Drosophila Toll receptor does not interact directly with microbial determinants, but is instead activated by a cleaved form of the cytokine-like molecule Spätzle. During the immune response, Spätzle is processed by complex cascades of serine proteases, which are activated by secreted pattern-rec...
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| Main Authors: | , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
National Academy of Sciences
2009
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2718337/ https://ncbi.nlm.nih.gov/pubmed/19590012 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0901924106 |
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