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A Look-Ahead Model for the Elongation Dynamics of Transcription

This article introduces a chemical kinetic model of the transcriptional elongation dynamics of RNA polymerase. The model's novel concept is a look-ahead feature, in which nucleotides bind reversibly to the DNA before being incorporated covalently into the nascent RNA chain. Analytical and compu...

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Detalhes bibliográficos
Main Authors: Yamada, Yujiro Richard, Peskin, Charles S.
Formato: Artigo
Idioma:Inglês
Publicado em: The Biophysical Society 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2718317/
https://ncbi.nlm.nih.gov/pubmed/19383448
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2008.12.3955
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