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Obstacles on the Microtubule Reduce the Processivity of Kinesin-1 in a Minimal In Vitro System and in Cell Extract

Inside cells, a multitude of molecular motors and other microtubule-associated proteins are expected to compete for binding to a limited number of binding sites available on microtubules. Little is known about how competition for binding sites affects the processivity of molecular motors and, theref...

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Bibliografiske detaljer
Main Authors: Telley, Ivo A., Bieling, Peter, Surrey, Thomas
Format: Artigo
Sprog:Inglês
Udgivet: The Biophysical Society 2009
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2718299/
https://ncbi.nlm.nih.gov/pubmed/19383477
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2009.01.015
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