Mal connects TLR2 to PI3Kinase activation and phagocyte polarization

The recognition of bacterial lipoproteins by toll-like receptor (TLR) 2 is pivotal for inflammation initiation and control in many bacterial infections. TLR2-dependent signalling is currently believed to essentially require both adaptor proteins MyD88 (myeloid differentiation primary response gene 8...

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Detalhes bibliográficos
Main Authors: Santos-Sierra, S, Deshmukh, S D, Kalnitski, J, Küenzi, P, Wymann, M P, Golenbock, D T, Henneke, Philipp
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2009
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2718282/
https://ncbi.nlm.nih.gov/pubmed/19574958
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/emboj.2009.158
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