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Diffusion in Cytoplasm: Effects of Excluded Volume Due to Internal Membranes and Cytoskeletal Structures

The intricate geometry of cytoskeletal networks and internal membranes causes the space available for diffusion in cytoplasm to be convoluted, thereby affecting macromolecule diffusivity. We present a first systematic computational study of this effect by approximating intracellular structures as mi...

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Autors principals: Novak, Igor L., Kraikivski, Pavel, Slepchenko, Boris M.
Format: Artigo
Idioma:Inglês
Publicat: The Biophysical Society 2009
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2718152/
https://ncbi.nlm.nih.gov/pubmed/19651034
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2009.05.036
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