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Diffusion in Cytoplasm: Effects of Excluded Volume Due to Internal Membranes and Cytoskeletal Structures

The intricate geometry of cytoskeletal networks and internal membranes causes the space available for diffusion in cytoplasm to be convoluted, thereby affecting macromolecule diffusivity. We present a first systematic computational study of this effect by approximating intracellular structures as mi...

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Detalhes bibliográficos
Main Authors: Novak, Igor L., Kraikivski, Pavel, Slepchenko, Boris M.
Formato: Artigo
Idioma:Inglês
Publicado em: The Biophysical Society 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2718152/
https://ncbi.nlm.nih.gov/pubmed/19651034
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2009.05.036
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