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Age-dependent disease expression determines remodeling of the retinal mosaic in carriers of RPGR exon ORF15 mutations
PURPOSE: To characterize the retinal histopathology in carriers of X-linked progressive retinal atrophy (XLPRA1 & XLPRA2), two canine models of X-linked retinitis pigmentosa caused, respectively, by a stop and a frameshift mutation in RPGRORF15. METHODS: Retinas of XLPRA2 and XLPRA1 carriers of...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2009
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2718058/ https://ncbi.nlm.nih.gov/pubmed/19255154 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1167/iovs.08-3364 |
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