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Serum Myeloperoxidase Levels Independently Predict Endothelial Dysfunction in Humans

BACKGROUND: In vitro and animal studies demonstrate that myeloperoxidase catalytically consumes nitric oxide as a substrate, limiting its bioavailability and function. We therefore hypothesized that circulating levels of myeloperoxidase would predict risk of endothelial dysfunction in human subjects...

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Detalhes bibliográficos
Main Authors: Vita, Joseph A., Brennan, Marie-Luise, Gokce, Noyan, Mann, Shirley A., Goormastic, Marlene, Shishehbor, Mehdi H., Penn, Marc S., Keaney, John F., Hazen, Stanley L.
Formato: Artigo
Idioma:Inglês
Publicado em: 2004
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2718053/
https://ncbi.nlm.nih.gov/pubmed/15326065
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/01.CIR.0000140262.20831.8F
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