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Cell-surface targeting of α(2)-adrenergic receptors — Inhibition by a transport deficient mutant through dimerization

We previously demonstrated that the α(2B)-adrenergic receptor mutant, in which the F(x)(6)IL motif in the membrane-proximal carboxyl terminus were mutated to alanines (α(2B)-ARm), is deficient in export from the endoplasmic reticulum (ER). In this report, we determined if α(2B)-ARm could modulate tr...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Zhou, Fuguo, Filipeanu, Catalin M., Duvernay, Matthew T., Wu, Guangyu
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2005
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2718052/
https://ncbi.nlm.nih.gov/pubmed/15961277
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cellsig.2005.05.014
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