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Estradiol Increases Guanosine 5′-Triphosphate Cyclohydrolase Expression Via the Nitric Oxide-Mediated Activation of Cyclic Adenosine 5′-Monophosphate Response Element Binding Protein

A number of studies have demonstrated that estradiol can stimulate endothelial nitric oxide synthase expression and activity, resulting in enhanced nitric oxide (NO) generation. However, its effect on the NO synthase cofactor, tetrahydrobiopterin are less clear. Cellular tetrahydrobiopterin levels a...

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Detalhes bibliográficos
Main Authors: Sun, Xutong, Kumar, Sanjiv, Tian, Jing, Black, Stephen M.
Formato: Artigo
Idioma:Inglês
Publicado em: The Endocrine Society 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2717883/
https://ncbi.nlm.nih.gov/pubmed/19389836
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/en.2008-1464
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