Activation of the Lutropin/Choriogonadotropin Receptor Inhibits Apoptosis of Immature Leydig Cells in Primary Culture

Eitemau Tebyg

• Lutropin/choriogonadotropin (LH/CG) stimulate the proliferation of primary cultures of rat Leydig cells through a pathway that involves activation of the ERK1/2 cascade
  gan: Shiraishi, Koji, et al.
  Cyhoeddwyd: (2007)
• Potential Leydig cell mitogenic signals generated by the wild-type and constitutively active mutants of the lutropin/choriogonadotropin receptor (LHR)
  gan: Ascoli, Mario
  Cyhoeddwyd: (2006)
• Activation of the lutropin/choriogonadotropin receptor (LHR) in MA-10 cells stimulates tyrosine kinase cascades that activate Ras and the extracellular signal regulated kinases (ERK1/2).
  gan: Shiraishi, Koji, et al.
  Cyhoeddwyd: (2006)
• A co-coculture system reveals the involvement of intercellular pathways as mediators of the lutropin receptor (LHR)-stimulated ERK1/2 phosphorylation in Leydig cells
  gan: Shiraishi, Koji, et al.
  Cyhoeddwyd: (2007)
• Mutations of the lutropin/choriogonadotropin receptor that do not activate the phosphoinositide cascade allow hCG to induce aromatase expression in immature rat granulosa cells
  gan: Andric, Nebojsa, et al.
  Cyhoeddwyd: (2008)