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Insulin and Insulin-Like Growth Factor-I Receptors Differentially Mediate Insulin-Stimulated Adhesion Molecule Production by Endothelial Cells

Patients with type 2 diabetes are hyperinsulinemic and insulin resistant and develop premature atherosclerosis. High concentrations of insulin stimulate the production of adhesion molecules by endothelial cells (ECs). ECs express abundant IGF-I receptors as well as insulin receptors. Whether IGF-I r...

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Bibliografiske detaljer
Main Authors: Li, Guolian, Barrett, Eugene J., Ko, Seung-Hyun, Cao, Wenhong, Liu, Zhenqi
Format: Artigo
Sprog:Inglês
Udgivet: The Endocrine Society 2009
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2717867/
https://ncbi.nlm.nih.gov/pubmed/19423756
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/en.2009-0172
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