ESR1 Promoter Hypermethylation Does Not Predict Atypia in RPFNA nor Persistent Atypia after 12 Months Tamoxifen Chemoprevention

PURPOSE: Currently, we lack biomarkers to predict whether high-risk women with mammary atypia will respond to tamoxifen chemoprevention. EXPERIMENTAL DESIGN: Thirty-four women with cytologic mammary atypia from the Duke University High-Risk clinic were offered tamoxifen chemoprevention. We tested wh...

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Autori principali: Baker, Joseph C., Ostrander, Julie H., Lem, Siya, Broadwater, Gloria, Bean, Gregory R., D'Amato, Nicholas C., Goldenberg, Vanessa K., Rowell, Craig, Ibarra-Drendall, Catherine, Grant, Tracey, Pilie, Patrick G., Vasilatos, Shauna N., Troch, Michelle M., Scott, Victoria, Wilke, Lee G., Paisie, Carolyn, Rabiner, Sarah M., Torres-Hernandez, Alejandro, Zalles, Carola M., Seewaldt, Victoria L.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2008
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2717700/
https://ncbi.nlm.nih.gov/pubmed/18708376
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1055-9965.EPI-07-2696
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