Clinical Significance of Epigenetic Inactivation of hMLH1 and BRCA1 in Tunisian Patients with Invasive Breast Carcinoma

Aberrant hypermethylation of gene promoter regions is one of the mechanisms for inactivation of tumour suppressor genes in many human cancers including breast carcinoma. In the current study, we aimed to assess by MSP, the methylation pattern of two cancer-related genes involved in DNA repair: hMLH1...

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Hlavní autoři: Karray-Chouayekh, Sondes, Trifa, Fatma, Khabir, Abdelmajid, Boujelbane, Nouredine, Sellami-Boudawara, Tahia, Daoud, Jamel, Frikha, Mounir, Gargouri, Ali, Mokdad-Gargouri, Raja
Médium: Artigo
Jazyk:Inglês
Vydáno: Hindawi Publishing Corporation 2009
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Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2717605/
https://ncbi.nlm.nih.gov/pubmed/19644562
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2009/369129
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