Characterization of highly stable liposomal and immunoliposomal formulations of vincristine and vinblastine

PURPOSE: Liposome and immunoliposome formulations of two vinca alkaloids, vincristine and vinblastine, were prepared using intraliposomal triethylammonium sucroseoctasulfate and examined for their ability to stabilize the drug for targeted drug delivery in vivo. METHODS: The pharmacokinetics of both...

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Hlavní autoři: Noble, Charles O., Guo, Zexiong, Hayes, Mark E., Marks, James D., Park, John W., Benz, Christopher C., Kirpotin, Dmitri B., Drummond, Daryl C.
Médium: Artigo
Jazyk:Inglês
Vydáno: Springer-Verlag 2009
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Original Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2717390/
https://ncbi.nlm.nih.gov/pubmed/19184019
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00280-008-0923-3
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