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Thermodynamic Effects of Noncoded and Coded Methionine Substitutions in Calmodulin
The methionine residues in the calcium (Ca(2+)) regulatory protein calmodulin (CaM) are structurally and functionally important. They are buried within the N- and C-domains of apo-CaM but become solvent-exposed in Ca(2+)-CaM, where they interact with numerous target proteins. Previous structural stu...
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| Hauptverfasser: | , , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
The Biophysical Society
2009
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2717255/ https://ncbi.nlm.nih.gov/pubmed/19217866 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2008.10.060 |
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