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Nitric Oxide in VEGF-induced Focal Angiogenesis and Matrix Metalloproteinase-9 Activity in the Mouse Brain

BACKGROUND: Vascular endothelial growth factor (VEGF) can induce matrix metalloproteinase (MMP)-9 activities and focal angiogenesis. We hypothesized that VEGF activation of cerebral MMP-9 would require nitric oxide (NO) participation. METHODS: We compared the in vivo effects of: (1) N(G)-monomethyl-...

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Detalhes bibliográficos
Main Authors: Lee, Chanhung Z., Xue, Zheng, Hao, Qi, Yang, Guo-Yuan, Young, William L.
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2717176/
https://ncbi.nlm.nih.gov/pubmed/19498186
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/STROKEAHA.109.552059
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