ATR Mutation in Endometrioid Endometrial Cancer Is Associated With Poor Clinical Outcomes

PURPOSE: Mutations in the DNA damage response gene ATR (exon 10 A10 mononucleotide repeat) have been previously described in endometrial and other cancers with defective DNA mismatch repair. In vitro studies showed that endometrial cancer cell lines with A10 repeat tract truncating mutations have a...

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Autores principales: Zighelboim, Israel, Schmidt, Amy P., Gao, Feng, Thaker, Premal H., Powell, Matthew A., Rader, Janet S., Gibb, Randall K., Mutch, David G., Goodfellow, Paul J.
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society of Clinical Oncology 2009
Materias:
Original Reports
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC2716934/
https://ncbi.nlm.nih.gov/pubmed/19470935
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1200/JCO.2008.19.9802
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