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Primary resistance, multidrug resistance, and cross-resistance pathways in HBV as a consequence of treatment failure

Antiviral resistance is now the single most important factor in treatment failure using nucleos(t)ide analogues (NA). Primary drug resistance mutations refer to amino acid change(s) that result in reduced susceptibility to an antiviral agent. Secondary compensatory mutations restore replication defe...

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Bibliografski detalji
Glavni autor: Locarnini, Stephen
Format: Artigo
Jezik:Inglês
Izdano: Springer-Verlag 2008
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2716855/
https://ncbi.nlm.nih.gov/pubmed/19669299
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s12072-008-9048-3
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