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Primary resistance, multidrug resistance, and cross-resistance pathways in HBV as a consequence of treatment failure

Antiviral resistance is now the single most important factor in treatment failure using nucleos(t)ide analogues (NA). Primary drug resistance mutations refer to amino acid change(s) that result in reduced susceptibility to an antiviral agent. Secondary compensatory mutations restore replication defe...

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Detalhes bibliográficos
Autor principal: Locarnini, Stephen
Formato: Artigo
Idioma:Inglês
Publicado em: Springer-Verlag 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2716855/
https://ncbi.nlm.nih.gov/pubmed/19669299
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s12072-008-9048-3
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