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Primary resistance, multidrug resistance, and cross-resistance pathways in HBV as a consequence of treatment failure
Antiviral resistance is now the single most important factor in treatment failure using nucleos(t)ide analogues (NA). Primary drug resistance mutations refer to amino acid change(s) that result in reduced susceptibility to an antiviral agent. Secondary compensatory mutations restore replication defe...
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| Formato: | Artigo |
| Idioma: | Inglês |
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Springer-Verlag
2008
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| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2716855/ https://ncbi.nlm.nih.gov/pubmed/19669299 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s12072-008-9048-3 |
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