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Procaine inhibits the proliferation and DNA methylation in human hepatoma cells
PURPOSE: Transcriptional silencing of tumor suppressor genes associated with DNA hypermethylation has been known as a hallmark of human cancer. In this study, we revealed that a local anesthetic, procaine (PCA), possessed growth-inhibitory and demethylating effect on human hepatoma cells in vitro an...
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| Main Authors: | , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Springer-Verlag
2007
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2716835/ https://ncbi.nlm.nih.gov/pubmed/19669330 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s12072-007-9014-5 |
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