Interferon-beta is activated by hepatitis C virus NS5B and inhibited by NS4A, NS4B, and NS5A

Innate immunity is part of the antiviral response. Interferon (IFN)-beta plays a leading role in this system. To investigate the influence of hepatitis C virus (HCV) on innate immunity, we examined the effect of viral proteins on IFN-beta induction. HepG2 cells were co-transfected with plasmids for...

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Detalhes bibliográficos
Main Authors: Moriyama, Masaru, Kato, Naoya, Otsuka, Motoyuki, Shao, Run-Xuan, Taniguchi, Hiroyoshi, Kawabe, Takao, Omata, Masao
Formato: Artigo
Idioma:Inglês
Publicado em: Springer-Verlag 2007
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Original Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2716828/
https://ncbi.nlm.nih.gov/pubmed/19669354
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s12072-007-9003-8
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