Association of IL-18 promoter polymorphism with liver disease severity in HCV-infected patients

INTRODUCTION: Interleukin (IL)-18 plays an important dual role in Th1 polarization and viral clearance, as well as in the development of liver fibrosis. Single-nucleotide promoter polymorphisms influence the transcription of IL-18 mRNA. Promoter polymorphisms are linked to delayed virus clearance an...

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Main Authors: Manohar, K., Suneetha, P. V., Sukriti, Pati, Nirupama Trehan, Gupta, Abhishek C., Hissar, Syed, Sakhuja, Puja, Sarin, S. K.
Formato: Artigo
Idioma:Inglês
Publicado em: Springer-Verlag 2009
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Original Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2716760/
https://ncbi.nlm.nih.gov/pubmed/19669363
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s12072-009-9127-0
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