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Cardioprotective effects of 3-methyl-1-phenyl-2-pyrazolin-5-one (MCI-186), a novel free radical scavenger, on acute autoimmune myocarditis in rats

BACKGROUND: Recent evidence suggests that oxidative stress may play a role in myocarditis. PURPOSE: To test the hypothesis that 3-methyl-1-phenyl-2-pyrazolin-5-one (edaravone or MCI-186), a novel free radical scavenger, protects against acute experimental autoimmune myocarditis (EAM) in rats. METHOD...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Okabe, Taka-aki, Kishimoto, Chiharu, Hattori, Miki, Nimata, Masaomi, Shioji, Keisuke, Kita, Toru
Format: Artigo
Sprache:Inglês
Veröffentlicht: Pulsus Group Inc 2004
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2716743/
https://ncbi.nlm.nih.gov/pubmed/19641722
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