Fold-Unfold Transitions in the Selectivity and Mechanism of Action of the N-Terminal Fragment of the Bactericidal/Permeability-Increasing Protein (rBPI(21))

Septic or endotoxic shock is a common cause of death in hospital intensive care units. In the last decade numerous antimicrobial peptides and proteins have been tested in the search for an efficient drug to treat this lethal disease. Now in phase III clinical trials, rBPI(21), a recombinant N-termin...

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Detaylı Bibliyografya
Asıl Yazarlar: Domingues, Marco M., Lopes, Sílvia C.D.N., Santos, Nuno C., Quintas, Alexandre, Castanho, Miguel A.R.B.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: The Biophysical Society 2009
Konular:
Membrane
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC2716647/
https://ncbi.nlm.nih.gov/pubmed/19186136
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2008.10.044
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