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Preparation of chitosan-polyaspartic acid-5-fluorouracil nanoparticles and its anti-carcinoma effect on tumor growth in nude mice

AIM: To prepare chitosan-polyaspartic acid-5-fluorouracil (CTS-Pasp-5Fu) nanoparticles and investigate its anti-carcinoma effect and toxicity. METHODS: CTS-Pasp-5Fu nanoparticles were synthesized by ionic gelatification. Male BABL/c nude mice were injected with SGC-7901 gastric carcinoma cell line m...

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Detalhes bibliográficos
Main Authors: Zhang, Dan-Ying, Shen, Xi-Zhong, Wang, Ji-Yao, Dong, Ling, Zheng, Yong-Li, Wu, Li-Li
Formato: Artigo
Idioma:Inglês
Publicado em: The WJG Press and Baishideng 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2716620/
https://ncbi.nlm.nih.gov/pubmed/18567086
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3748/wjg.14.3554
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