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L.E.A.P.S. heteroconjugate is able to prevent and treat experimental autoimmune myocarditis by altering trafficking of autoaggressive cells to the heart
We evaluated the efficacy of the Ligand Epitope Antigen Presentation System (L.E.A.P.S.(™)) in preventing or treating experimental autoimmune myocarditis (EAM) in A/J mice. L.E.A.P.S. (here, J-My-1) is a conjugate of the myocarditogenic peptide of cardiac myosin MyHCα(334–352) (My-1) and J peptide,...
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| Main Authors: | , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2008
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2716547/ https://ncbi.nlm.nih.gov/pubmed/18387504 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.intimp.2008.01.004 |
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