Epidermal Growth Factor Receptor Inhibition Modulates the Microenvironment by Vascular Normalization to Improve Chemotherapy and Radiotherapy Efficacy

BACKGROUND: Epidermal growth factor receptor (EGFR) inhibitors have shown only modest clinical activity when used as single agents to treat cancers. They decrease tumor cell expression of hypoxia-inducible factor 1-α (HIF-1α) and vascular endothelial growth factor (VEGF). Hypothesizing that this mig...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Cerniglia, George J., Pore, Nabendu, Tsai, Jeff H., Schultz, Susan, Mick, Rosemarie, Choe, Regine, Xing, Xiaoman, Durduran, Turgut, Yodh, Arjun G., Evans, Sydney M., Koch, Cameron J., Hahn, Stephen M., Quon, Harry, Sehgal, Chandra M., Lee, William M. F., Maity, Amit
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Public Library of Science 2009
Pynciau:
Research Article
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC2716529/
https://ncbi.nlm.nih.gov/pubmed/19657384
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0006539
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