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Targeting inhibitor of apoptosis proteins in combination with ErbB antagonists in breast cancer

INTRODUCTION: Inhibitor of apoptosis (IAPs) proteins are a family of proteins that can block apoptosis in normal cells and have been suggested to cause resistance to apoptosis in cancer. Overexpression of oncogenic receptor tyrosine kinases is common in breast cancer; in particular 20% of all cases...

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Detalhes bibliográficos
Main Authors: Foster, Fiona M, Owens, Thomas W, Tanianis-Hughes, Jolanta, Clarke, Robert B, Brennan, Keith, Bundred, Nigel J, Streuli, Charles H
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2716510/
https://ncbi.nlm.nih.gov/pubmed/19563669
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/bcr2328
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