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Changing the Mechanical Unfolding Pathway of FnIII(10) by Tuning the Pulling Strength

We investigate the mechanical unfolding of the tenth type III domain from fibronectin (FnIII(10)) both at constant force and at constant pulling velocity, by all-atom Monte Carlo simulations. We observe both apparent two-state unfolding and several unfolding pathways involving one of three major, mu...

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Detalles Bibliográficos
Main Authors: Mitternacht, Simon, Luccioli, Stefano, Torcini, Alessandro, Imparato, Alberto, Irbäck, Anders
Formato: Artigo
Idioma:Inglês
Publicado: The Biophysical Society 2009
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2716458/
https://ncbi.nlm.nih.gov/pubmed/19167294
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2008.09.043
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