No association of CDK5 genetic variants with Alzheimer's disease risk

BACKGROUND: As cyclin-dependent kinase 5 (CDK5) has been implicated in the abnormal hyperphosphorylation of tau in Alzheimer's disease (AD) brain, and the development of neurofibrillary tangles, we examined the contribution of this gene to the susceptibility for AD. METHODS: We examined genetic...

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Autors principals: Vázquez-Higuera, José Luis, Mateo, Ignacio, Sánchez-Juan, Pascual, Rodríguez-Rodríguez, Eloy, Infante, Jon, Berciano, José, Combarros, Onofre
Format: Artigo
Idioma:Inglês
Publicat: BioMed Central 2009
Matèries:
Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2716333/
https://ncbi.nlm.nih.gov/pubmed/19615060
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2350-10-68
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