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Candesartan augments ischemia-induced proangiogenic state and results in sustained improvement after stroke

OBJECTIVE: We have shown that acute treatment with candesartan in an experimental model of stroke resulted in vascular protection and improved outcomes at 24 hours post-stroke, but the mechanisms are unknown. We now examine effects of candesartan on proangiogenic factors and 7-day outcomes using the...

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Detalhes bibliográficos
Main Authors: Kozak, Anna, Ergul, Adviye, El-Remessy, Azza B., Johnson, Maribeth H., Machado, Livia S., Elewa, Hazem F., Abdelsaid, Mohammed, Wiley, Daniel C., Fagan, Susan C.
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2716175/
https://ncbi.nlm.nih.gov/pubmed/19265050
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/STROKEAHA.108.537225
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