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Pregnancy modifies the large conductance Ca(2+)-activated K(+) channel and cGMP-dependent signaling pathway in uterine vascular smooth muscle

Regulation of uteroplacental blood flow (UPBF) during pregnancy remains unclear. Large conductance, Ca(2+)-activated K(+) channels (BK(Ca)), consisting of α- and regulatory β-subunits, are expressed in uterine vascular smooth muscle (UVSM) and contribute to the maintenance of UPBF in the last third...

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Autors principals: Rosenfeld, Charles R., Liu, Xiao-tie, DeSpain, Kevin
Format: Artigo
Idioma:Inglês
Publicat: American Physiological Society 2009
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2716109/
https://ncbi.nlm.nih.gov/pubmed/19470517
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpheart.01185.2008
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