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Participation of Mammalian Target of Rapamycin Complex 1 in Toll-Like Receptor 2– and 4–Induced Neutrophil Activation and Acute Lung Injury

mTOR complex 1 (mTORC1) plays a central role in cell growth and cellular responses to metabolic stress. Although mTORC1 has been shown to be activated after Toll-like receptor (TLR)-4 engagement, there is little information concerning the role that mTORC1 may play in modulating neutrophil function a...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Lorne, Emmanuel, Zhao, Xia, Zmijewski, Jaroslaw W., Liu, Gang, Park, Young-Jun, Tsuruta, Yuko, Abraham, Edward
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Thoracic Society 2009
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2715911/
https://ncbi.nlm.nih.gov/pubmed/19131641
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1165/rcmb.2008-0290OC
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