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Utilizing Ras Signaling Pathway to Direct Selective Replication of Herpes Simplex Virus-1

Re-engineering the tropism of viruses is an attractive translational strategy for targeting cancer cells. The Ras signal transduction pathway is a central hub for a variety of pro-oncogenic events with a fundamental role in normal and neoplastic physiology. In this work we were interested in linking...

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Hlavní autoři: Pan, Weihong, Bodempudi, Vidya, Esfandyari, Tuba, Farassati, Faris
Médium: Artigo
Jazyk:Inglês
Vydáno: Public Library of Science 2009
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2715884/
https://ncbi.nlm.nih.gov/pubmed/19652721
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0006514
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