Serine 58 of 14-3-3ζ Is a Molecular Switch Regulating ASK1 and Oxidant Stress-Induced Cell Death

Oxidant stress is a ubiquitous stressor with negative impacts on multiple cell types. ASK1 is a central mediator of oxidant injury, but while mechanisms of its inhibition, such as sequestration by 14-3-3 proteins and thioredoxin, have been identified, mechanisms of activation have remained obscure a...

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Autores principales: Zhou, Jibin, Shao, Zhili, Kerkela, Risto, Ichijo, Hidenori, Muslin, Anthony J., Pombo, Celia, Force, Thomas
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society for Microbiology (ASM) 2009
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Articles
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC2715813/
https://ncbi.nlm.nih.gov/pubmed/19451227
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.01067-08
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