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Nipah Virus Sequesters Inactive STAT1 in the Nucleus via a P Gene-Encoded Mechanism

The Nipah virus (NiV) phosphoprotein (P) gene encodes the C, P, V, and W proteins. P, V, and W, have in common an amino-terminal domain sufficient to bind STAT1, inhibiting its interferon (IFN)-induced tyrosine phosphorylation. P is also essential for RNA-dependent RNA polymerase function. C is enco...

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Detalhes bibliográficos
Main Authors: Ciancanelli, Michael J., Volchkova, Valentina A., Shaw, Megan L., Volchkov, Viktor E., Basler, Christopher F.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology (ASM) 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2715789/
https://ncbi.nlm.nih.gov/pubmed/19515782
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.02610-08
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