Activation of Intracellular Signaling Pathways by the Murine Cytomegalovirus G Protein-Coupled Receptor M33 Occurs via PLC-β/PKC-Dependent and -Independent Mechanisms

The presence of numerous G protein-coupled receptor (GPCR) homologs within the herpesvirus genomes suggests an essential role for these genes in viral replication in the infected host. Such is the case for murine cytomegalovirus (MCMV), where deletion of the M33 GPCR or replacement of M33 with a sig...

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Detalhes bibliográficos
Main Authors: Sherrill, Joseph D., Stropes, Melissa P., Schneider, Olivia D., Koch, Diana E., Bittencourt, Fabiola M., Miller, Jeanette L. C., Miller, William E.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology (ASM) 2009
Assuntos:
Virus-Cell Interactions
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2715766/
https://ncbi.nlm.nih.gov/pubmed/19494016
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.02116-08
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