Synthetic Peptide Vaccine Targeting a Cryptic Neutralizing Epitope in Domain 2 of Bacillus anthracis Protective Antigen

Current evidence suggests that protective antigen (PA)-based anthrax vaccines may elicit a narrow neutralizing antibody repertoire, and this may represent a vulnerability with PA-based vaccines. In an effort to identify neutralizing specificities which may complement those prevalent in PA antiserum,...

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Detalhes bibliográficos
Main Authors: Oscherwitz, Jon, Yu, Fen, Jacobs, Jana L., Liu, Te-Hui, Johnson, Philip R., Cease, Kemp B.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology (ASM) 2009
Assuntos:
Microbial Immunity and Vaccines
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2715696/
https://ncbi.nlm.nih.gov/pubmed/19487468
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.00358-09
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