Interval-Specific Congenic Lines Reveal Quantitative Trait Loci with Penetrant Lyme Arthritis Phenotypes on Chromosomes 5, 11, and 12

The observation that Borrelia burgdorferi-induced arthritis is severe in C3H mice and milder in C57BL/6 (B6) mice has allowed a forward genetics approach for the identification of genetic elements that regulate the arthritis response. Quantitative trait loci (QTL) on five chromosomes (Chr) were iden...

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Main Authors: Ma, Ying, Miller, Jennifer C., Crandall, Hillary, Larsen, Eric T., Dunn, Diane M., Weiss, Robert B., Subramanian, Meenakumari, Weis, John H., Zachary, James F., Teuscher, Cory, Weis, Janis J.
Formáid: Artigo
Teanga:Inglês
Foilsithe: American Society for Microbiology (ASM) 2009
Ábhair:
Bacterial Infections
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC2715682/
https://ncbi.nlm.nih.gov/pubmed/19487472
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.00396-09
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