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Daptomycin Rapidly Penetrates a Staphylococcus epidermidis Biofilm

Fluorescently tagged daptomycin accessed the interior of Staphylococcus epidermidis biofilm cell clusters within minutes. The diffusion coefficient of daptomycin in the biofilm was 28% of its value in pure water. Daptomycin activity against staphylococci embedded in biofilms is unlikely to be limite...

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Detalhes bibliográficos
Main Authors: Stewart, Philip S., Davison, William M., Steenbergen, Judith N.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology (ASM) 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2715639/
https://ncbi.nlm.nih.gov/pubmed/19451285
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.01728-08
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