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Anidulafungin Treatment of Candidal Central Nervous System Infection in a Murine Model

We established a murine model of Candida albicans central nervous system (CNS) infection and evaluated the efficacy of anidulafungin. Ten milligrams/kg/day anidulafungin, amphotericin B, or voriconazole significantly reduced mortality and fungal burden in brain tissue, although amphotericin B and 10...

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Detalhes bibliográficos
Main Authors: Kang, Cheol-In, Rouse, Mark S., Mandrekar, Jayawant N., Steckelberg, James M., Patel, Robin
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology (ASM) 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2715626/
https://ncbi.nlm.nih.gov/pubmed/19506064
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.00646-09
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