Analysis of Single-Nucleotide Polymorphisms in the crt-o and mdr1 Genes of Plasmodium vivax among Chloroquine-Resistant Isolates from the Brazilian Amazon Region

Plasmodium vivax parasites with chloroquine resistance (CQR) are already circulating in the Brazilian Amazon. Complete single-nucleotide polymorphism (SNP) analyses of coding and noncoding sequences of the pvmdr1 and pvcrt-o genes revealed no associations with CQR, even if some mutations had not bee...

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Hlavní autoři: Orjuela-Sánchez, Pamela, de Santana Filho, Franklin Simões, Machado-Lima, Ariane, Chehuan, Yonne Francis, Costa, Mônica Regina Farias, Alecrim, Maria das Graças Costa, del Portillo, Hernando A.
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Microbiology (ASM) 2009
Témata:
Mechanisms of Resistance
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2715622/
https://ncbi.nlm.nih.gov/pubmed/19451296
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.00004-09
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