Peptide-Lipid Huge Toroidal Pore, a New Antimicrobial Mechanism Mediated by a Lactococcal Bacteriocin, Lacticin Q

Lacticin Q is a pore-forming bacteriocin produced by Lactococcus lactis QU 5, and its antimicrobial activity is in the nanomolar range. Lacticin Q induced calcein leakage from negatively charged liposomes. However, no morphological changes in the liposomes were observed by light scattering. Concomit...

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Bibliographic Details
Main Authors: Yoneyama, Fuminori, Imura, Yuichi, Ohno, Kanako, Zendo, Takeshi, Nakayama, Jiro, Matsuzaki, Katsumi, Sonomoto, Kenji
Format: Artigo
Language:Inglês
Published: American Society for Microbiology (ASM) 2009
Subjects:
Mechanisms of Action: Physiological Effects
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2715615/
https://ncbi.nlm.nih.gov/pubmed/19470516
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.00209-09
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