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Reception of Slit requires only the chondroitin–sulphate-modified extracellular domain of Syndecan at the target cell surface

Syndecan (Sdc) is a conserved transmembrane heparan sulfate proteoglycan (HSPG) bearing additional chondroitin sulfate (CS) modifications on its extracellular domain. In vertebrates, this extracellular domain of Sdc is shed and acts as a soluble effector of cellular communication events, and its cyt...

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Hlavní autoři: Chanana, Bhavna, Steigemann, Patrick, Jäckle, Herbert, Vorbrüggen, Gerd
Médium: Artigo
Jazyk:Inglês
Vydáno: National Academy of Sciences 2009
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2715486/
https://ncbi.nlm.nih.gov/pubmed/19574454
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0901148106
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