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The Effect of Cyclosporin A on Airway Cell Proinflammatory Signaling and Pneumonia
Cyclosporin A (CsA) blocks T cell activation by interfering with the Ca(2+)-dependent phosphatase, calcineurin. Proinflammatory responses to bacteria that are activated by Ca(2+)-fluxes in airway cells are a potential target for CsA. Although local immunosuppression may be advantageous to control ai...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
American Thoracic Society
2005
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2715308/ https://ncbi.nlm.nih.gov/pubmed/15879161 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1165/rcmb.2005-0005OC |
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